Company Filing History:
Years Active: 2001
Title: Simon Charles Dolan: Innovator in Phosphonium Compounds
Introduction
Simon Charles Dolan is a notable inventor based in Rickmansworth, GB. He has made significant contributions to the field of chemistry, particularly in the preparation of phosphonium compounds. His work has implications for the development of glycine antagonists, which are important in various therapeutic applications.
Latest Patents
Dolan holds a patent for the "Preparation of phosphonium compounds as intermediates for glycine antagonists." This patent describes a process for preparing a specific phosphonium compound by reacting N-phenylpyrrolidinone with pyridinium bromide perbromide, in the presence of a tertiary organic base and a suitable Lewis acid. The resultant bromo derivative is then treated with phosphine to yield the desired compound, which can be utilized in the preparation of glycine antagonists.
Career Highlights
Simon Charles Dolan is associated with Glaxo Wellcome Spa, where he applies his expertise in chemical processes. His innovative approach to synthesizing phosphonium compounds has positioned him as a valuable asset in the pharmaceutical industry.
Collaborations
Dolan has collaborated with notable colleagues, including Paolo Maragni and Alcide Perboni. These partnerships have likely contributed to the advancement of his research and the successful development of his patented processes.
Conclusion
Simon Charles Dolan's work in the field of phosphonium compounds exemplifies the impact of innovative thinking in chemistry. His contributions continue to influence the development of important therapeutic agents.