Company Filing History:
Years Active: 2023
Title: Shunchang Jiao: Innovator in Biotechnology
Introduction
Shunchang Jiao is a prominent inventor based in Beijing, China. He has made significant contributions to the field of biotechnology, particularly in the development of innovative methods for cancer treatment and vaccine preparation. With a total of 2 patents, his work is at the forefront of medical research.
Latest Patents
One of Jiao's latest patents is the LRFFT2 cell. This invention utilizes human peripheral blood for ctDNA sequencing or tumor tissues for whole exome sequencing. It screens out mutation sites to perform antigen epitope prediction and synthesizes an expression gene sequence of mutant peptides. Additionally, it constructs a lentiviral vector, packages the lentivirus, and transfects an APC cell to complete the transformation of a specific LV cell. This process involves co-culturing in vitro with PBMC separated from peripheral blood to screen out effective polypeptides and transform common T cells into RFF cells. The invention also addresses suppressive signaling molecules, including PD-1, Tim-3, LAG3, CTLA-4, BTLA, VISTA, CD160, and 2B4 (CD244), as well as various antigen-presenting cells.
Another significant patent is the coronavirus-targeting universal DC cell vaccine. This invention provides a method for preparing a vaccine that targets coronaviruses, belonging to the technical field of virus vaccine preparation. The preparation method involves ligating a fusion gene that includes an HLA gene and a coronavirus antigen gene onto an expression vector to create a recombinant vector. This vector is then transferred into antigen-presenting cells to obtain the coronavirus-targeting universal DC cell vaccine. This vaccine effectively stimulates CTLs and demonstrates a killing effect on target cells.
Career Highlights
Shunchang Jiao has worked with Beijing Dcty Biotech Co., Ltd., where he has contributed to various innovative projects. His expertise in biotechnology has positioned him as a key player in the development of advanced medical solutions.
Collaborations
Some of his notable coworkers include Rong Zhang and Zishan Zhou, who have collaborated with him on various projects in the field of biotechnology.
Conclusion
Shunchang Jiao's contributions to biotechnology, particularly in cancer treatment and vaccine development, highlight his innovative spirit and dedication to advancing medical science. His patents reflect a