The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2023

Filed:

Aug. 10, 2020
Applicants:

Beijing Dcty Biotech Co., Ltd., Beijing, CN;

Shunchang Jiao, Beijing, CN;

Inventors:

Shunchang Jiao, Beijing, CN;

Rong Zhang, Beijing, CN;

Zishan Zhou, Beijing, CN;

Assignees:

Beijing DCTY Biotech Co., Ltd., Beijing, CN;

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); A61K 39/215 (2006.01); A61P 31/14 (2006.01); C07K 14/165 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61P 31/14 (2018.01); C07K 14/165 (2013.01); C12N 15/86 (2013.01);
Abstract

The present invention provides a method for preparing a coronavirus-targeting universal DC cell vaccine, and belongs to the technical field of virus vaccine preparation. The preparation method includes the following steps: ligating a fusion gene including a HLA gene and a coronavirus antigen gene onto an expression vector to obtain a recombinant vector; then transferring the recombinant vector into antigen-presenting cells to be transfected to obtain the coronavirus-targeting universal DC cell vaccine. The universal DC cell vaccine of the present invention has a targeting property against a coronavirus, can effectively stimulate a CTL, and has a killing effect on a target cell.


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