Shuangying Gui

Title: Innovations of Shuangying Gui in Hydrogel Microneedles

Introduction

Shuangying Gui is an innovative inventor based in Hefei, China. He has made significant contributions to the field of biomedical engineering, particularly in the development of hydrogel microneedles. His work focuses on improving drug delivery systems, which can enhance patient care and treatment efficacy.

Latest Patents

Shuangying Gui holds a patent for a "Colchicine hydrogel microneedle and preparation method thereof." This patent describes a novel preparation method for colchicine hydrogel microneedles, which includes several steps. The process involves dissolving acrylamide, N,N'-bis(acryloyl)cysteamine, and Irgacure 2959 in ultrapure water to create a clear gel solution. This solution is then poured into a polydimethylsiloxane mold, followed by low-speed centrifugation and ultrasonic treatment to remove air bubbles. The mold is irradiated under ultraviolet light and air-dried to produce the hydrogel microneedle. Finally, a colchicine solution is added to the hydrogel microneedle, allowing it to swell, air-dry, and be demolded. This innovative method addresses the issue of uneven cross-linking points in traditional hydrogel microneedles, resulting in a product with a complete needle shape, neat matrix arrangement, evenly distributed cross-linking points, excellent mechanical toughness, and superior swelling capacity.

Career Highlights

Throughout his career, Shuangying Gui has worked with notable institutions, including Anhui University of Chinese Medicine and Anhui Baicaojingyan Pharmaceutical Technology Co., Ltd. His experience in these organizations has allowed him to refine his skills and contribute to advancements in pharmaceutical technology.

Collaborations

Shuangying Gui has collaborated with talented individuals such as Can Peng and Huanhuan Liu. These partnerships have fostered a creative environment that encourages innovation and the development of new technologies.

Conclusion

Shuangying Gui's contributions to the field of hydrogel microneedles represent a significant advancement in drug delivery systems. His innovative methods and collaborative efforts continue to pave the way for future developments in biomedical engineering.