This inventor holds 2 USPTO granted patents. Top assignee: Adimab, LLC. Active years: 2016-2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- San Jose, CA (US) (2016)
- Cupertino, CA (US) (2019)
Company Filing History:
Years Active: 2016-2019
Title: Shuanghong Wei: Innovator in Antibody Engineering
Introduction
Shuanghong Wei is a prominent inventor based in Cupertino, CA, known for his significant contributions to the field of antibody engineering. With a total of 2 patents to his name, he has made strides in developing methods for generating high-affinity humanized antibodies.
Latest Patents
Wei's latest patents focus on the high throughput generation and affinity maturation of humanized antibodies. These patents provide compositions, methods, and kits for efficiently generating and screening humanized antibodies with high affinity against specific antigens. The library of humanized antibodies is created by mutagenizing a chimeric antibody template that combines the human antibody framework with antigen-binding sites from non-human antibodies. Alternatively, the library can be generated by grafting essential antigen-recognition segments, such as CDRs from non-human antibodies, into the corresponding positions of a human antibody library. This library is then screened for high-affinity binding toward specific antigens, either in vivo using organisms like yeast or in vitro through techniques such as ribosome display or mRNA display. The entire process is designed to be efficient, high throughput, and automated, effectively mimicking the natural process of antibody affinity maturation.
Career Highlights
Shuanghong Wei is currently employed at Adimab, LLC, where he continues to advance the field of antibody research. His work has been instrumental in developing innovative solutions that enhance the efficacy of therapeutic antibodies.
Collaborations
Wei collaborates with notable colleagues, including Li Zhu and Shaobing Benjamin Hua, contributing to a dynamic research environment that fosters innovation.
Conclusion
Shuanghong Wei's work in antibody engineering exemplifies the impact of innovative research on therapeutic development. His patents and contributions are paving the way for advancements in medical science and treatment options.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile