Company Filing History:
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2 out of 24 Years Active: 2022-2024
Title: **Innovative Contributions of Shuai Liu in Bioengineering**
Introduction
Shuai Liu, an accomplished inventor from Henan, China, has made significant contributions to the field of bioengineering, particularly in the production of L-theanine. With a total of two patents, his innovative methods showcase advancements in fermentation technology that promise both efficiency and high-quality yield.
Latest Patents
Liu’s latest patents focus on a groundbreaking method for producing L-theanine via fermentation utilizing a genetically engineered bacterium. The engineered strain, derived from an original W3110 genome, integrates several genetic modifications, including a single copy of T7RNAP and a dual copy of gmas, while also performing knockout functions on xylR and sucCD genes. This innovative approach enables a fermentation process that yields L-theanine at an impressive titer of 75-80 g/L within 20-25 hours, achieving a yield rate of 52-55%. The meticulous purification of the fermentation broth employs membrane separation and cation-anion resin techniques, culminating in a one-step crystallization yield of 72.3% and a final product purity of 99%.
Career Highlights
Throughout his career, Shuai Liu has collaborated with significant companies in the industry. Notably, he has worked at Henan Julong Biological Engineering Co., Ltd, where his expertise in bioengineering flourished. Additionally, his academic pursuits at Tianjin University of Science and Technology have further enhanced his knowledge and innovation capabilities.
Collaborations
Shuai Liu has been fortunate to collaborate with talented professionals in his field, including Xiaoguang Fan and Xiaodong Liu. Their combined expertise contributes to the overall advancement of the technologies and methods they pursue.
Conclusion
Shuai Liu's pioneering work in the method of producing L-theanine through genetically engineered microorganisms marks a significant step forward in bioengineering. His innovations not only demonstrate the potential for high yields in fermentation processes but also pave the way for future research and application in the field. As he continues to develop and refine his techniques, the impact of his contributions is sure to resonate throughout the industry and academic realms.