Location History:
- Fayetteville, NY (US) (1989 - 1996)
- Lawrenceville, NJ (US) (1997)
Company Filing History:
Years Active: 1989-1997
Title: Shreeram N Agharkar: Innovator in Pharmaceutical Formulations
Introduction
Shreeram N Agharkar is a notable inventor based in Fayetteville, NY (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of stable injectable formulations for anticancer agents. With a total of 5 patents, Agharkar's work has the potential to enhance the efficacy and shelf life of critical medications.
Latest Patents
One of Agharkar's latest patents is the "Stable injectable formulation of BMY-25067." This invention focuses on creating a stable and easy-to-constitute injectable formulation of the anticancer agent BMY-25067. The formulation is derived from lyophilizing a solution that contains up to 4 mg of BMY-25067 per mL of a 65% t-butanol/water mixture, along with about 2% PVP (K-12 or K-17) and optionally includes pharmaceutically acceptable carriers.
Another significant patent is the "Stabilized pharmaceutical composition and stabilizing solvent." This invention involves a stabilized pharmaceutical composition that includes paclitaxel, teniposide, camptothecin, or other antineoplastic agents that are prone to degradation during storage. The solvent system used in this composition consists of a mixture of ethanol and polyoxyethylated castor oil, which has been treated to reduce carboxylate anion content. This innovative approach provides an extended shelf life and minimizes degradation by-products.
Career Highlights
Throughout his career, Agharkar has worked with prominent companies such as Bristol-Myers Squibb Company and Bristol-Myers Company. His experience in these organizations has allowed him to refine his expertise in pharmaceutical formulations and contribute to groundbreaking innovations in the field.
Collaborations
Agharkar has collaborated with notable coworkers, including Uday S Gogate and Joseph B Bogardus. These partnerships have facilitated the exchange of ideas and expertise, further enhancing the quality of his inventions.
Conclusion
Shreeram N Agharkar is a distinguished inventor whose work in pharmaceutical formulations has the potential to significantly impact cancer treatment. His innovative patents and collaborations reflect his commitment to advancing medical science and improving patient outcomes.