Company Filing History:
Years Active: 1992-2000
Title: Shoshana Bascomb: Innovator in Antibiotic Resistance Testing
Introduction
Shoshana Bascomb is a notable inventor based in Davis, CA, who has made significant contributions to the field of antibiotic resistance testing. With a total of five patents to her name, she has developed innovative methods that enhance the detection and understanding of bacterial resistance to antibiotics.
Latest Patents
Among her latest patents is the "Rapid Inducible Beta-Lactamase Screen Test." This assay determines beta-lactam antibiotic resistance in target bacterial strains by growing them in the presence of both a beta-lactamase inducing antibiotic and a beta-lactam indicator antibiotic. The growth of the strain, indicative of drug resistance, is monitored by detecting a fluorophore released through enzymatic cleavage of a metabolizable fluorogenic compound. Another significant patent involves a method for measuring color reactions by monitoring changes in fluorescence. This invention allows for the determination of the concentration of an unknown substance in a colorimetric reaction using a fluorometric reader, where the change in fluorescence is proportional to the intensity of color in the reaction.
Career Highlights
Shoshana has worked with prominent companies such as Baxter Diagnostics Inc. and Dade Microscan Inc., where she has applied her expertise in developing innovative solutions for medical diagnostics. Her work has been instrumental in advancing the understanding of antibiotic resistance, which is a critical issue in healthcare today.
Collaborations
Throughout her career, Shoshana has collaborated with notable colleagues, including Roger J. Morris and Carolyn S. Olson, who have contributed to her research and development efforts.
Conclusion
Shoshana Bascomb's contributions to the field of antibiotic resistance testing through her innovative patents and collaborations highlight her role as a leading inventor in this critical area of research. Her work continues to impact the medical community and improve diagnostic methods for antibiotic resistance.