Location History:
- Niihari-mura, JP (2006)
- Ibaraki, JP (2005 - 2008)
- Kanagawa, JP (2005 - 2012)
Company Filing History:
6 out of 950 
3 out of 14 
1 out of 1 Years Active: 2005-2012
Title: Innovations and Contributions of Inventor Shoji Miyata
Introduction
Shoji Miyata is a distinguished inventor hailing from Kanagawa, Japan, recognized for his considerable contributions to the field of bioscience. With a remarkable portfolio consisting of seven patents, he has made significant strides in understanding protein functions, particularly those related to smooth muscle cell differentiation.
Latest Patents
Miyata's latest patents showcase his pioneering work on critical proteins and their implications for health. One notable patent focuses on an antibody directed to a protein involved in maintaining the differentiation of smooth muscle cells. In this invention, a cDNA fragment was isolated from chicken gizzard smooth muscle cells using a specialized culture system and innovative methods such as differential display and subtracted hybridization. This research led to the identification of a novel gene, 'C-NT2RP3001495', which encodes a protein featuring two WW domains that facilitate protein interactions in the N-terminal domain. This protein is crucial in regulating intracellular signal transduction and gene expression, thereby impacting smooth muscle cell differentiation. The development of drugs targeting this protein and its expression holds promise for treating diseases linked to abnormalities in smooth muscle cell maintenance.
Another significant patent by Miyata pertains to antibodies targeting a brain-specific membrane protein. This work involved constructing a cDNA library derived from mRNA expressed in the human adult brain, which successfully isolated a gene that encodes a transmembrane glycoprotein. The encoded protein exhibits brain-specific expression and contains a typical PDZ binding motif, further expanding our understanding of neuronal processes.
Career Highlights
Throughout his career, Shoji Miyata has been associated with prominent companies such as Chugai Seiyaku Kabushiki Kaisha, which has allowed him to translate his research into practical solutions within the pharmaceutical industry. His innovative spirit and dedication to research have garnered him recognition and respect among his peers in the scientific community.
Collaborations
Miyata's collaborations with esteemed coworkers, including Shin-Ichi Funahashi and Toshio Ota, have further enriched his research endeavors. These partnerships have fostered a collaborative environment conducive to innovation and have enhanced the development of impactful solutions in bioscience.
Conclusion
In summary, Shoji Miyata's contributions to the field of bioscience through his patents and collaborations reflect a profound commitment to understanding protein functions and their relevance to health. His latest inventions highlight the potential for significant advancements in drug development aimed at treating diseases resulting from smooth muscle cell differentiation abnormalities. As a dedicated inventor, Miyata continues to inspire future innovations within the scientific community.