Shoba Amarnath

Title: Shoba Amarnath: Innovator in Immunology

Introduction

Shoba Amarnath is a prominent inventor based in Washington, DC, known for her significant contributions to the field of immunology. With a focus on T cell regulation, she has developed innovative methods that have the potential to transform therapeutic approaches in various medical conditions.

Latest Patents

Shoba Amarnath holds two patents that highlight her groundbreaking work. Her latest patent involves the use of PDL1 expressing cells to convert T cells into regulatory T cells. This invention provides methods and compositions for converting a T cell into a cell that exhibits at least one regulatory T cell phenotype. The converted T cell is generated by contacting a T cell with a cell that is modified to comprise an agent capable of activating PD1 signaling in a T cell. The converted T cell is useful for preventing, suppressing, blocking, or inhibiting an immune response. For example, the converted T cell is useful for preventing rejection of a transplanted tissue in a human or other animal host, or protecting against graft versus host disease. Additionally, the converted T cell can also be used to treat autoimmune diseases.

Career Highlights

Throughout her career, Shoba Amarnath has worked with esteemed institutions such as the University of Pennsylvania and the National Institutes of Health, a component of the US Department of Health & Human Services. Her work in these organizations has allowed her to advance her research and contribute to significant scientific advancements.

Collaborations

Shoba has collaborated with notable colleagues, including James L. Riley and Daniel H. Fowler, further enhancing her research and innovation in the field of immunology.

Conclusion

Shoba Amarnath's contributions to immunology through her patents and collaborations underscore her role as a leading inventor in the field. Her innovative approaches to T cell regulation hold promise for future medical therapies.