Company Filing History:
Years Active: 2019-2020
Title: Shino Hanabuchi: Innovator in Autoimmunity Treatment
Introduction
Shino Hanabuchi is a notable inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of immunology, particularly in the treatment of autoimmune diseases. With a total of 2 patents, his work focuses on innovative methods to enhance immune responses without compromising the host's immune system.
Latest Patents
Hanabuchi's latest patents include the development of antagonistic anti-OX40L antibodies and methods of their use. These antibodies are designed to treat autoimmunity and inflammatory conditions effectively. The unique aspect of these anti-OX40L antibodies is their dual functionality; they inhibit the differentiation of inflammatory T cells while promoting the generation and function of regulatory T cells. This is achieved by inducing IL-10 and inhibiting TNF-α, as well as reducing aberrant Th2 cell responses. Furthermore, the methods and compositions described in his patents aim to eliminate or reduce aberrant T follicular helper cell (Tfh) responses, which can contribute to the pathogenicity of autoimmune diseases.
Career Highlights
Shino Hanabuchi is currently associated with Baylor Research Institute, where he continues to advance his research in immunology. His work has garnered attention for its potential to revolutionize treatment approaches for autoimmune conditions.
Collaborations
One of his notable collaborators is Sandra M Zurawski, who contributes to the research efforts alongside Hanabuchi.
Conclusion
Shino Hanabuchi's innovative work in the field of immunology, particularly through his patents on anti-OX40L antibodies, showcases his commitment to improving treatment options for autoimmune diseases. His contributions are paving the way for more effective therapies that enhance immune regulation without compromising overall health.