Shigetada Nakanishi

Title: Shigetada Nakanishi: Innovator in Endothelin Receptor Research

Introduction

Shigetada Nakanishi is a prominent inventor based in Kyoto, Japan. He has made significant contributions to the field of biochemistry, particularly in the study of endothelin receptors. With a total of 6 patents to his name, Nakanishi's work has advanced our understanding of these critical receptors.

Latest Patents

Nakanishi's latest patents focus on the human endothelin receptor. The DNA encoding this receptor, as shown in SEQ ID NO: 1 or 2 in the Sequence Listing, is isolated from cDNA prepared from poly(A) RNA derived from human placenta. An expression vector containing this DNA and a transformant containing the expression vector are obtained. The endothelin receptor is produced by culturing this transformant. The receptor shown in SEQ ID NO: 1 is an ET-receptor with a high affinity for endothelins 1 and 2, particularly for endothelin 1. Conversely, the receptor shown in SEQ ID NO: 2 is an ET-receptor that exhibits affinity for endothelins 1, 2, and 3 without selectivity.

Career Highlights

Throughout his career, Nakanishi has worked with notable companies such as Shionogi Pharmaceutical Co., Ltd. and Mitsubishi Chemical Corporation. His experience in these organizations has allowed him to apply his research in practical settings, contributing to advancements in medical science.

Collaborations

Nakanishi has collaborated with esteemed colleagues, including Hiroo Imura and Kazuwa Nakao. These partnerships have fostered innovation and have been instrumental in the development of his research.

Conclusion

Shigetada Nakanishi's work in endothelin receptor research has made a lasting impact on the field of biochemistry. His patents and collaborations highlight his dedication to advancing scientific knowledge and improving healthcare outcomes.