Location History:
- College Station, TX (US) (2017)
- Starkville, MS (US) (2018 - 2024)
Company Filing History:
4 out of 173 
3 out of 5,463 
Years Active: 2017-2024
Title: Shien Lu: Innovator in Antifungal Research
Introduction
Shien Lu is a notable inventor based in Starkville, MS (US). He has made significant contributions to the field of antifungal research, holding a total of 4 patents. His work focuses on enhancing the efficacy of antifungal treatments, particularly through the development of occidiofungin formulations.
Latest Patents
One of Shien Lu's latest patents involves engineering the production of a conformational variant of occidiofungin that exhibits enhanced inhibitory activity against various fungal species. Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide known for its submicromolar activity. This invention encompasses compositions enriched for specific occidiofungin diastereomers/conformers, methods for creating these enriched compositions, and microorganisms suitable for their production. Additionally, methods for treating fungal infections or plants infected by fungi are also included.
Another significant patent pertains to occidiofungin formulations and their applications in treating proliferative disorders, such as cancer. This patent outlines methods for producing these formulations, which may include occidiofungin combined with one or more cyclodextrins. The formulations can also incorporate additional chemotherapeutic agents, lipid vesicles, and/or aqueous solvents, including pharmaceutically acceptable buffers and excipients.
Career Highlights
Shien Lu has had a distinguished career, contributing to research and innovation in antifungal treatments. He has worked at prominent institutions, including Mississippi State University and The Texas A&M University System. His research has led to advancements in the understanding and treatment of fungal infections and related disorders.
Collaborations
Shien Lu has collaborated with notable colleagues, including James Leif Smith and Ganyu Gu, who is a woman. These collaborations have further enriched his research and contributed to the development of innovative solutions in the field.
Conclusion
Shien Lu's work in antifungal research and his innovative patents highlight his commitment to advancing medical treatments. His contributions are paving the way for more effective therapies against fungal infections and proliferative disorders.