The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 23, 2019

Filed:

Sep. 14, 2015
Applicants:

Mississippi State University, Starkville, MS (US);

The Texas A&m University System, College Station, TX (US);

Inventors:

James L. Smith, College Station, TX (US);

Stephen Pruett, Starkville, MS (US);

Frank Austin, Starkville, MS (US);

Shien Lu, Starkville, MS (US);

Ravichandran Akshaya, Bryan, TX (US);

Steven Laihing, College Station, TX (US);

Assignees:

MISSISSIPPI STATE UNIVERSITY, Starkville, MS (US);

THE TEXAS A&M UNIVERSITY SYSTEM, College Station, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); A61K 45/06 (2006.01); A61K 47/40 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 9/127 (2006.01); A61K 31/724 (2006.01);
U.S. Cl.
CPC ...
A61K 38/12 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 9/127 (2013.01); A61K 31/724 (2013.01); A61K 45/06 (2013.01); A61K 47/40 (2013.01);
Abstract

Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of treating a subject with the formulations are provided. In some embodiments, the formulations include occidiofungin and one or more cyclodextrins. The formulations may optionally further comprise an additional chemotherapeutic agent for treating the proliferative disease, lipid vesicles, and/or aqueous solvents (including pharmaceutically acceptable buffers and/or exceipients).


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