Shibo Jiang

Title: Shibo Jiang: Innovator in Fusion Proteins and Ketoamide Compounds

Introduction

Shibo Jiang is a prominent inventor based in Shanghai, China. He has made significant contributions to the fields of biotechnology and pharmaceuticals, holding three patents that showcase his innovative work. His research focuses on developing novel compounds that can combat serious viral infections.

Latest Patents

One of Shibo Jiang's latest patents is titled "Fusion protein and use thereof." This patent describes a fusion protein that includes a trimerization block and an immunogenic block connected by a linker. The immunogenic block is derived from a pathogen, such as a coronavirus RBD block, an HIV membrane protein, or an influenza virus hemagglutinin protein. This trimeric structure is designed to generate a higher neutralizing antibody level compared to a monomer, while also promoting a more focused immune response.

Another significant patent is for a "Ketoamide compound and preparation method, pharmaceutical composition, and use thereof." This patent details a ketoamide compound that can effectively inhibit both coronavirus and Ebola virus. The compound can be presented in various forms, including racemates, enantiomers, or pharmaceutically active metabolites, making it versatile for therapeutic applications.

Career Highlights

Shibo Jiang has worked at esteemed institutions such as Fudan University and the Chinese Academy of Sciences. His research has been pivotal in advancing our understanding of viral mechanisms and developing potential treatments.

Collaborations

Shibo Jiang has collaborated with notable colleagues, including Zezhong Liu and Lu Lu. Their combined expertise has contributed to the success of various research projects and patent applications.

Conclusion

Shibo Jiang's innovative work in fusion proteins and ketoamide compounds highlights his significant impact on biotechnology and pharmaceuticals. His patents not only advance scientific knowledge but also hold promise for future therapeutic developments.