Sherry Niessen

Title: Sherry Niessen: Innovator in Cancer Research

Introduction

Sherry Niessen is a prominent inventor based in San Diego, CA (US). She has made significant contributions to the field of cancer research, particularly through her innovative work on enzyme regulation in ether lipid signaling pathways. Her research has implications for understanding aggressive cancer cell behavior and potential therapeutic targets.

Latest Patents

Sherry Niessen holds a patent for her work titled "Enzyme regulating ether lipid signaling pathways." This patent describes a multidimensional profiling strategy that combines activity-based proteomics and metabolomics. The research identifies an active protein, previously uncharacterized, that is highly elevated in aggressive cancer cells. This protein serves as a central node in an ether lipid signaling network, bridging platelet-activating factor and lysophospholipids. Biochemical studies have confirmed that this active protein regulates the pathway by hydrolyzing the metabolic intermediate 2-acetyl monoalkylglycerol. Inactivation of this protein disrupts ether lipid metabolism in cancer cells, impairing cell migration and tumor growth in vivo.

Career Highlights

Sherry Niessen is affiliated with The Scripps Research Institute, where she conducts her research. Her work has garnered attention for its innovative approach to understanding cancer biology and potential treatment strategies.

Collaborations

Sherry has collaborated with notable researchers in her field, including Benjamin F. Cravatt and Kyle P. Chiang. These collaborations have further enhanced the impact of her research and contributed to advancements in cancer treatment.

Conclusion

Sherry Niessen's innovative research and patent contributions are paving the way for new insights into cancer biology and potential therapeutic interventions. Her work exemplifies the critical role of inventors in advancing scientific knowledge and improving health outcomes.