Company Filing History:
3 out of 459 
3 out of 14 
1 out of 14 
Years Active: 1988-1997
Title: Innovations in Immunology: The Contributions of Sheldon M. Wolff
Introduction: Sheldon M. Wolff, based in Norfolk County, MA, has made significant strides in the field of immunology through his innovative research and inventions. With a total of three patents to his name, his work primarily focuses on the development of antibodies related to interleukin-1, a crucial component in immune response.
Latest Patents: Wolff's latest patents include the groundbreaking inventions related to antibodies targeting IL-1. The first patent involves a nucleic acid comprising a nucleotide sequence that encodes human interleukin-1 (IL-1), alongside the polypeptides and peptides derived from it. This invention emphasizes the cloning of cDNA synthesized from poly(A)RNA derived from human monocytes stimulated by bacterial endotoxin. The IL-1 protein is instrumental in inducing the production of IL-2 by activated T-cells and also impacts B-cells and natural killer (NK) cells. His second patent mirrors the first, confirming the scope and relevance of human IL-1 in immunological responses.
Career Highlights: Throughout his career, Sheldon M. Wolff has been affiliated with prestigious institutions including Tufts College and Wellesley College. His work in these academic settings has not only fostered his personal research endeavors but has also contributed to the broader scientific community's understanding of immune mechanisms.
Collaborations: Wolff's research journey has been enriched by collaborations with esteemed colleagues such as Philip E. Auron and Charles A. Dinarello. These partnerships have facilitated the exchange of knowledge and expertise, further propelling advances in immunology and related fields.
Conclusion: Sheldon M. Wolff's contributions to immunology, particularly through his patents on antibodies to IL-1.beta., exemplify his commitment to enhancing our understanding of immune responses. His career, underscored by collaboration and innovation, continues to inspire future research in the field. As the landscape of immunological study evolves, Wolff's inventions remain pivotal in bridging fundamental research with practical applications in health and medicine.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.