Shean Jen Chen

Title: Innovations of Shean Jen Chen in Surface Plasmon Resonance Microscopy

Introduction

Shean Jen Chen is a notable inventor based in Jhongli, Taiwan. He has made significant contributions to the field of microscopy, particularly through his innovative work in surface plasmon resonance technology. His research focuses on enhancing the capabilities of microscopy for biomolecular interaction analysis.

Latest Patents

Shean Jen Chen holds a patent for a "Surface plasmon resonance microscope using common-path phase-shift interferometry." This invention integrates surface plasmon resonance and common-path phase-shift interferometry techniques to develop a microscope capable of measuring two-dimensional spatial phase variations caused by biomolecular interactions on a sensing chip. Notably, this method eliminates the need for additional labeling, which is a significant advancement in the field. The microscope demonstrates a detection limit of 2×10 refractive index change, a long-term phase stability of 2.5×10π rms over four hours, and a spatial phase resolution of 10π with a lateral resolution of 100 μm.

Career Highlights

Shean Jen Chen is associated with Phalanx Biotech Group, Inc., where he continues to push the boundaries of research in biotechnology and microscopy. His work has been instrumental in developing tools that facilitate real-time kinetic studies in biomolecular interaction analysis.

Collaborations

He collaborates with Yuan Deng Su, contributing to advancements in their shared field of research. Their partnership exemplifies the importance of teamwork in driving innovation.

Conclusion

Shean Jen Chen's contributions to surface plasmon resonance microscopy represent a significant leap forward in the analysis of biomolecular interactions. His innovative approach and dedication to research continue to influence the field positively.