This inventor holds 5 USPTO granted patents and 16 published patent applications and 1 EPO patent. Top assignee: Renovo Limited. Active years: 2009-2011.
Location History:
- Derbyshire, GB (2009)
- Manchester, GB (2010 - 2011)
Company Filing History:
Years Active: 2009-2011
Title: Innovations by Sharon O'Kane
Introduction
Sharon O'Kane is a prominent inventor based in Manchester, GB. She has made significant contributions to the field of biotechnology, particularly in the development of therapeutic proteins. With a total of 5 patents to her name, her work has the potential to impact medical treatments significantly.
Latest Patents
One of her latest patents involves TGF-β3 mutants. This invention provides TGF-β3s, or fragments or derivatives thereof, wherein the alpha-helix-forming domain between amino acid residues (58) and (67) of full-length wild type TGF-β3 comprises at least one alpha-helix-stabilizing substitution. Additionally, the invention includes TGF-β3s, or fragments or derivatives thereof, wherein the Glycine residue at position (63) of full-length wild type TGF-β3 is replaced with Proline. Furthermore, it provides TGF-β3s, or fragments or derivatives thereof, comprising a substitution of the Glutamic acid residue at position (12) and/or the Arginine residue at position (52) of full-length wild type TGF-β3. The invention also encompasses medicaments and methods of treatment using such TGF-β3s.
Another significant patent focuses on medicaments and proteins based on TGF-β monomers for the treatment of wounds. This patent provides the use of monomeric TGF-βs, or their fragments or derivatives, as medicaments. These medicaments preferably comprise monomeric TGF-β3, or fragments or derivatives thereof. The medicaments provided may be used in the acceleration of wounding and/or the inhibition of scarring, in the promotion of epithelial regeneration, or in the prevention and/or treatment of fibrotic disorders.
Career Highlights
Sharon O'Kane is currently associated with Renovo Limited, where she continues to innovate in the field of biotechnology. Her work has garnered attention for its potential applications in medical treatments and regenerative medicine.
Collaborations
Sharon has collaborated with notable professionals in her field, including Hugh Gerard Laverty and Nick Occleston. These collaborations have further enhanced her research and development efforts.
Conclusion
Sharon O'Kane's contributions to biotechnology through her patents and innovative work