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Title: Shadma Ashraf: Pioneering Innovations in Rabies Vaccination
Introduction
Shadma Ashraf is an accomplished inventor based in Uttar Pradesh, India, known for her groundbreaking work in vaccine development. With one patented invention, Shadma has made significant strides in enhancing the efficacy of rabies vaccinations through innovative biotechnology involving transgenic plants.
Latest Patents
Shadma's most significant patent is the "Chimeric G Protein-Based Rabies Vaccine." This innovative vaccine features a novel chimeric protein of the rabies virus designed to express a chimeric G protein at a high level in transgenic plants. The process involved the design and chemical synthesis of a gene encoding the chimeric G protein, which was expressed in transgenic tobacco plants. The results demonstrated that the chimeric G protein enriched in plant membranes could serve as a commercially valuable subunit vaccine, eliciting a stronger immune response than traditional commercial vaccines when tested on BalbC mice.
Career Highlights
Shadma's career has been marked by her impactful contributions to the field of biotechnology. She has collaborated extensively with reputable institutions such as the Council of Scientific & Industrial Research and Unichem Laboratories Limited. Through these roles, she has gained a wealth of experience and expertise in research and development, particularly in vaccine technology.
Collaborations
Throughout her career, Shadma has worked closely with notable colleagues, including Rakesh Tuli and Samir Vishwanath Sawant. These collaborations have fostered a dynamic environment for innovation, allowing her to pursue and achieve groundbreaking research goals.
Conclusion
Shadma Ashraf stands out as a leading figure in biotechnological innovations, particularly in rabies vaccination. Her pioneering work involving the development of a chimeric G protein vaccine not only highlights her inventiveness but also underscores the potential for transgenic plants in medical applications. As the field of vaccine development continues to evolve, Shadma's contributions will undoubtedly inspire future innovations.