Sergey Lukianov

Title: Innovations of Sergey Lukianov

Introduction

Sergey Lukianov is a prominent inventor based in Moscow, Russia. He has made significant contributions to the field of molecular biology, particularly in the area of polymerase chain reaction (PCR) techniques. With a total of 2 patents, his work has advanced the specificity and sensitivity of DNA amplification methods.

Latest Patents

One of Sergey Lukianov's latest patents is a method for suppressing DNA fragment amplification during PCR. This invention pertains to novel materials and methods designed to suppress the amplification of specific DNA fragments during the PCR process. The method utilizes innovative adapters that are ligated to the ends of DNA fragments prior to amplification. Upon melting and annealing, these single-stranded DNA fragments can form suppressive 'pan-like' double-stranded structures, which effectively inhibit the amplification of the fragments. This method enhances the specificity and sensitivity of PCR amplification without requiring target DNA sequence information. It can be adapted for various PCR techniques and applications, making it a valuable contribution to the field.

Career Highlights

Sergey Lukianov is associated with Clontech Laboratories, Inc., where he continues to develop and refine his innovative techniques. His work has been instrumental in advancing PCR methodologies, which are widely used in genetic research and diagnostics.

Collaborations

Throughout his career, Sergey has collaborated with notable colleagues, including Alex Chenchik and Luda Diatchenko. These collaborations have further enriched his research and contributed to the development of effective PCR techniques.

Conclusion

Sergey Lukianov's contributions to the field of molecular biology, particularly through his innovative PCR methods, have made a significant impact. His patents reflect a commitment to enhancing the accuracy and efficiency of DNA amplification techniques.