Company Filing History:
Years Active: 2008-2015
Title: **Innovative Contributions of Sergey Gorlatov in Biopharmaceuticals**
Introduction
Sergey Gorlatov is a notable inventor based in Gaithersburg, MD, who has made significant contributions to the field of biopharmaceuticals. With an impressive portfolio of 9 patents, Gorlatov focuses on improving the efficacy of therapeutic antibodies through innovative alterations in their structure.
Latest Patents
Among his latest patents, Gorlatov has developed Fc region-containing polypeptides that exhibit improved effector function due to alterations in the extent of fucosylation. This invention relates to Fc region-containing polypeptides that enhance treatment options for cancer and other diseases by optimizing the binding capabilities of antibodies to both activating and inhibitory Fc receptors.
Another significant patent involves the identification and engineering of antibodies with variant Fc regions, which demonstrate an enhanced affinity for FcγRIIIA and/or FcγRIIA compared to their wild-type counterparts. This innovation is critical for improving therapeutic outcomes in treating diseases where heightened effector cell function is necessary, such as cancer and infectious diseases.
Career Highlights
Gorlatov currently works at MacroGenics, Inc., a company renowned for its commitment to developing innovative monoclonal antibody-based therapeutics. His expertise and groundbreaking inventions contribute significantly to the company's mission of advancing cancer care through unique biopharmaceutical solutions.
Collaborations
Throughout his career, Gorlatov has collaborated with notable professionals, including Jeffrey B. Stavenhagen and Christopher Rankin, to enhance the development and efficacy of therapeutic agents. These collaborations exemplify his dedication to pushing the boundaries of current medical treatments and improving patient outcomes.
Conclusion
Sergey Gorlatov’s inventive work in the realm of biopharmaceuticals significantly impacts the industry, showcasing his commitment to advancing therapeutic technologies. With a focus on enhancing antibody efficacy and understanding their mechanisms, Gorlatov continues to be a pivotal figure in innovative healthcare solutions. His patents pave the way for future advancements in treating a variety of diseases, marking him as a key contributor to medical science.