Sei Hien Lim

Title: Innovations by Sei Hien Lim

Introduction

Sei Hien Lim is a notable inventor based in Singapore, recognized for his contributions to the field of biotechnology. He holds 2 patents that showcase his innovative approach to solving complex biological challenges. His work primarily focuses on microfluidic technologies and methods for inducing angiogenesis.

Latest Patents

One of his latest patents is a microfluidic platform for investigating cell-based interactions. This platform features a chip base made of suitable plastics with appropriate optical properties. The chip base includes multiple ports in fluid communication with a microfluidic channel that contains a culture medium for holding cells. A gas-permeable laminate is bonded to the bottom surface of the chip base, enhancing its functionality. Each port has an internal inlet connecting it to the microfluidic channel and a trough for containing a small reservoir of culture medium fluid adjacent to the inlet. This design allows for the aspiration of culture medium from the microfluidic channel via the trough, improving the efficiency of cell culture experiments.

Another significant patent by Lim involves compositions and methods for neovascularization. This invention focuses on a method of inducing angiogenesis at a site in an individual in need. It comprises administering an effective amount of agents that induce hypoxia-inducible factor 1α (HIF-1α) locally to the site. Additionally, the invention includes methods for generating prevascularized tissue and creating a vascular network in a device.

Career Highlights

Sei Hien Lim has worked with prominent organizations such as Aim Biotech Pte. Ltd. and the National University of Singapore. His experience in these institutions has allowed him to collaborate on various innovative projects that push the boundaries of biotechnology.

Collaborations

Throughout his career, Lim has collaborated with talented individuals, including Andrea Pavesi and Swee Khuan Lim. These partnerships have contributed to the advancement of his research and the successful development of his patents.

Conclusion

Sei Hien Lim's innovative work in microfluidic technologies and angiogenesis methods highlights his significant contributions to biotechnology. His patents reflect a commitment to advancing scientific knowledge and improving medical applications.