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Years Active: 2020-2023
Title: Sedigheh Delmaghani: Innovator in Hearing Loss Treatment
Introduction
Sedigheh Delmaghani is a prominent inventor based in Paris, France. She has made significant contributions to the field of auditory health, particularly in the prevention and treatment of hearing loss and impairment. With a total of 2 patents, her work focuses on innovative solutions that address critical issues in auditory function.
Latest Patents
Delmaghani's latest patents revolve around the use of gasdermin, specifically gasdermin A, B, C, D, DFNA5, and DFNB59 (or pejvakin). These inventions aim to modulate cellular redox homeostasis, with a particular emphasis on pejvakin as an antioxidant. Additionally, her research includes a virally-mediated gene therapy designed to restore genetically-impaired auditory and vestibular functions in individuals suffering from Usher syndrome. This gene therapy utilizes an AAV2/8 vector that expresses at least one USH1 gene product, preferably SANS.
Career Highlights
Throughout her career, Delmaghani has worked with esteemed institutions such as Institut Pasteur and the Centre National de la Recherche Scientifique. Her research has significantly advanced the understanding of auditory health and has the potential to improve the quality of life for many individuals affected by hearing loss.
Collaborations
Some of her notable collaborators include Christine Petit and Paul Avan. Their combined expertise has contributed to the success of various research projects aimed at enhancing auditory function.
Conclusion
Sedigheh Delmaghani's innovative work in the field of hearing loss treatment showcases her dedication to improving auditory health through groundbreaking research and collaboration. Her contributions are paving the way for new therapeutic approaches that could benefit countless individuals.