Sebastian Hörner

Title: Innovator Spotlight: Sebastian Hörner - Pioneering RNA Formulations for Therapy

Introduction:

Sebastian Hörner, a renowned inventor based in Mainz, Germany, has made significant contributions to the field of pharmaceutical science. With a strong focus on RNA formulations for therapy, Hörner's innovative approaches have garnered attention in the medical and research communities.

Latest Patents:

1. Preparation and storage of liposomal RNA formulations suitable for therapy: Hörner's groundbreaking patent focuses on methods for preparing RNA lipoplex particles for effective delivery of RNA to target tissues following parenteral administration. This includes intravenous administration, with a key emphasis on industrial GMP-compliant processes. Moreover, the patent addresses storing RNA lipoplex particles without compromising product quality or RNA activity.

2. Formulation for administration of RNA: Hörner's second patent highlights compositions comprising polyplex formulations for delivering RNA to specific organs or cells post parenteral administration, particularly through intramuscular injection. The formulations feature polyplex particles from single-stranded RNA and a polyalkyleneimine, potentially encoding various proteins of interest for pharmaceutical applications. Additionally, the patent covers the production of pharmaceutical products containing RNA polyplex formulations for human or animal use.

Career Highlights:

Sebastian Hörner has made significant strides in his career, notably working with esteemed organizations such as Biontech SE and TRON-Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz gemeinnützige GmbH. His expertise in RNA formulations has led to pioneering advancements in therapeutic delivery mechanisms, setting new standards in the industry.

Collaborations:

Throughout his career, Hörner has collaborated with prominent colleagues such as Heinrich Haas and Isaac Hernan Esparza Borquez. These collaborations have facilitated the exchange of ideas, expertise, and resources, contributing to the successful development and implementation of innovative pharmaceutical solutions.

Conclusion:

Sebastian Hörner's dedication to revolutionizing RNA formulations for therapy exemplifies his commitment to advancing medical science. His patents stand as a testament to his ingenuity and drive to improve the efficacy of RNA-based therapies. As a respected figure in the pharmaceutical industry, Hörner continues to inspire and influence future innovation in the field of therapeutic RNA delivery.