The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2024
Filed:
Jan. 10, 2019
Biontech SE, Mainz, DE;
Tron—translationale Onkologie an Der Universitatsmedizin Der Johannes Gutenberg-universitat Mainz Ggmbh, Mainz, DE;
Ugur Sahin, Mainz, DE;
Heinrich Haas, Mainz, DE;
Annette Vogel, Mainz, DE;
Stephanie Erbar, Mainz, DE;
Kerstin Walzer, Mainz, DE;
Anne Schlegel, Mainz, DE;
Sebastian Hörner, Mainz, DE;
Jorge Herrero Moreno, Mainz, DE;
Thorsten Klamp, Mainz, DE;
Sebastian Kreiter, Mainz, DE;
Mustafa Diken, Mainz, DE;
Phillip Heller, Mainz, DE;
Abstract
The present invention relates to compositions comprising polyplex formulations for delivery of RNA to a target organ or a target cell after parenteral administration, in particular after intramuscular administration. More precisely, the present invention relates to formulations for administration of RNA such as self-replicating RNA, in particular by intramuscular injection. In more detail, the formulations comprise polyplex particles from single stranded RNA and a polyalkyleneimine.