Company Filing History:
Years Active: 2018
Title: Innovations in Plant-Based Pharmaceuticals: The Patented Work of Sean Winkle
Introduction
Sean Winkle, an accomplished inventor located in Mesa, AZ, has made significant strides in the field of biopharmaceuticals. With a focus on plant transient expression technology, his work highlights the potential of utilizing plants for the production of complex therapeutics, specifically through innovative vectors.
Latest Patents
Winkle holds a patent for a groundbreaking invention titled "Geminiviral vector for expression of rituximab." This patent describes a single vector or multiple separate vectors that contain two or more non-competing replicons for the transient expression of the heavy and light chains of Rituximab in plant leaves. The invention outlines the precise assembly of these subunit proteins into functional oligomeric structures to optimize expression. This system represents a significant advancement in plant transient expression technology, as it eliminates the necessity for non-competing viruses and enhances the realistic commercial application of the multi-replicon single vector system for producing Rituximab in plant cells.
Career Highlights
Winkle works at Arizona State University, where he applies his expertise to research and develop innovative solutions within the realm of plant-based therapies. His role has not only contributed to scientific advancements but has also paved the way for future applications in the medical field.
Collaborations
Throughout his career, Sean Winkle has collaborated with esteemed colleagues including Hugh S Mason and Charles Joel Arntzen. These partnerships have bolstered his research efforts and expanded the horizons of plant-based pharmaceutical development, allowing for a synergistic approach to tackling complex challenges in biotechnology.
Conclusion
Sean Winkle's pioneering work and unique patent on the Geminiviral vector showcase the exciting potential of plants as vehicles for producing life-saving therapies like Rituximab. His contributions to Arizona State University and his collaborations with fellow experts underscore the importance of innovation and teamwork in advancing the science of biopharmaceuticals. With continued research and development, Winkle's inventions may play a crucial role in the future of medical treatments.