The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 2018
Filed:
Jan. 22, 2014
The Arizona Board of Regents for and on Behalf of Arizona State University, Tempe, AZ (US);
Hugh Mason, Phoenix, AZ (US);
Charles Arntzen, Gold Canyon, AZ (US);
Sun Hee Rosenthal, Santa Ana, CA (US);
Sean Winkle, Mesa, AZ (US);
Andrew Diamos, Tempe, AZ (US);
Hugh Mason, Phoenix, AZ (US);
Charles Arntzen, Gold Canyon, AZ (US);
Sun Hee Rosenthal, Santa Ana, CA (US);
Sean Winkle, Mesa, AZ (US);
Andrew Diamos, Tempe, AZ (US);
Arizona Board of Regents on Behalf of Arizona State University, Tempe, AZ (US);
Abstract
A single vector or multiple separate vectors that contain two or more non-competing replicons for transient expression of the heavy and light chains of Rituximab inleaves is described. The correct assembly of these subunit proteins into functional oligomeric structures to optimize the expression is also described. This system advances plant transient expression technology by eliminating the need for non-competing viruses, and thus, enhances the realistic commercial application of the multi-replicon single vector system for producing Rituximab in plant cells.