Sean Armour

Title: **Sean Armour: Innovator in Genetic Engineering**

Introduction

Sean Armour is an accomplished inventor based in Holland, PA, who has made significant contributions to the field of genetic engineering. With one patent to his name, his work focuses on developments that can greatly impact therapeutic approaches to certain genetic disorders.

Latest Patents

Sean Armour holds a patent for "Codon-optimized acid alpha-glucosidase expression cassettes and methods of using same." This patent provides valuable nucleic acids encoding acid α-glucosidase (GAA). In particular embodiments, these nucleic acids demonstrate over 86% sequence identity to various sequences outlined in the patent. The innovation emphasizes the importance of having fewer than 127 CpG dinucleotides, aiming to enhance the expression and efficacy of acid α-glucosidase. Additionally, the patent encompasses expression cassettes, vectors, and methods for utilizing these nucleic acids, which are crucial for advancing research and potential therapies.

Career Highlights

Sean Armour's professional journey has seen him align with the mission and vision of Spark Therapeutics, Inc., a pioneering company focused on gene therapy. His groundbreaking work has positioned him as a key player in the innovation of genetic treatments, particularly in conditions that require precise molecular interventions.

Collaborations

At Spark Therapeutics, Inc., Sean collaborates with esteemed colleagues, including Xavier Anguela and Jayme Nordin. Together, they contribute to the company's dedication to developing transformative gene therapies that hold the promise of changing lives.

Conclusion

In conclusion, Sean Armour stands out as an inventive force in genetic research, with his work on acid α-glucosidase holding the potential for therapeutic breakthroughs. His association with Spark Therapeutics demonstrates a commitment to pushing the boundaries of science and innovation in the field of medicine.