Scott Lokey

Title: Scott Lokey: Innovator in Peptide Science

Introduction

Scott Lokey is a prominent inventor based in Santa Cruz, California. He has made significant contributions to the field of peptide science, particularly in the development of cell permeable cyclic peptide scaffolds and inhibitors of protein-processivity factor interactions. With a total of 2 patents, Lokey's work has the potential to impact various therapeutic areas.

Latest Patents

One of Lokey's latest patents is focused on cell permeable cyclic peptide scaffolds. This patent includes a hexapeptide composed of naturally or non-naturally occurring amino acids. The disclosure also covers pharmaceutical compositions that incorporate these cyclic peptide scaffolds along with pharmaceutically acceptable excipients. Additionally, methods for utilizing these cell permeable cyclic peptide scaffolds are described.

Another significant patent involves a structure-based approach to designing inhibitors of protein-processivity factor interactions. This method outlines the structure-based identification and selection of inhibitors that prevent processivity factor binding to proteins. The patent details the characterization of the protein/processivity factor interface and includes methods for inhibiting this binding. One embodiment features a class of peptidomimetics that mimic helical portions of proteins, along with methods for treating various diseases using these inhibitors.

Career Highlights

Scott Lokey has held positions at prestigious institutions, including the University of California and Harvard College. His work at these institutions has allowed him to collaborate with leading researchers and contribute to advancements in peptide science.

Collaborations

Throughout his career, Lokey has worked alongside notable colleagues such as Donald M Coen and James Hogle. These collaborations have further enriched his research and innovation in the field.

Conclusion

Scott Lokey's contributions to peptide science through his innovative patents and collaborations highlight his role as a key inventor in this area. His work continues to pave the way for new therapeutic approaches and advancements in medical science.