Location History:
- Baltimore, MD (US) (1998 - 1999)
- Pikesville, MD (US) (2016)
Company Filing History:
Years Active: 1998-2016
Title: The Innovative Contributions of Saul Roseman
Introduction
Saul Roseman is a notable inventor based in Baltimore, MD (US). He has made significant contributions to the field of biotechnology, particularly in the conversion of chitin into valuable compounds. With a total of 3 patents, his work has implications for both environmental sustainability and biofuel production.
Latest Patents
One of Roseman's latest patents focuses on the "Conversion of chitin into N-acetylglucosamine, glucosamine and bioethanol." This invention provides compositions and methods for converting chitin, which can be sourced from invertebrate cuticles, fungal cells, and algae, into N-acetylglucosamine, glucosamine, and ethanol. The process involves creating mutant bacteria by knocking out or inactivating specific genes, allowing for the chitin catabolic sensor to maintain an activated state. Additionally, methods for converting N-acetylglucosamine into ethanol using a genetically engineered yeast strain are also described.
Another significant patent addresses the "Bacterial catabolism of chitin." This invention identifies three genes involved in the catabolism of chitin in Vibrio furnissii. The genes include endI, which encodes periplasmic chitodextrinase, exoI, which encodes periplasmic β-N-acetylglucosaminidase, and exoII, which encodes aryl β-N-acetylglucosaminidase. The complete nucleotide sequences and amino acids for these enzymes are provided, along with host cells capable of expressing the recombinant enzymes.
Career Highlights
Saul Roseman has worked with prestigious organizations such as Johns Hopkins University and New England Biolabs, Inc. His research has contributed to advancements in biotechnology and environmental science.
Collaborations
Throughout his career, Roseman has collaborated with esteemed colleagues, including Bonnie Bassler and Nemat O Keyhani. These partnerships have further enriched his research and innovations.
Conclusion
Saul Roseman's work exemplifies the intersection of innovation and environmental sustainability. His patents not only advance scientific knowledge but also offer practical solutions for utilizing chitin in biofuel production.