The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

Apr. 16, 2010
Applicants:

Saul Roseman, Pikesville, MD (US);

Dorinda A. Gershman, Cleveland Heights, OH (US);

Xibing LI, Phoenix, MD (US);

Donald Comb, Manchester, MA (US);

Inventors:

Saul Roseman, Pikesville, MD (US);

Xibing Li, Phoenix, MD (US);

Donald Comb, Manchester, MA (US);

Assignees:

The Johns Hopkins University, Baltimore, MD (US);

New England Biolabs, Ipswich, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12P 19/26 (2006.01); C12P 39/00 (2006.01); C12P 7/08 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12N 15/52 (2013.01); C12P 7/08 (2013.01); C12P 19/26 (2013.01); C12P 39/00 (2013.01); Y02E 50/17 (2013.01);
Abstract

Compositions and methods are provided for converting chitin into N-acetylglucosamine, glucosamine and ethanol. The chitin may be used directly from the environment, for example, as occurs in invertebrate cuticles, fungal cells and/or algae. Mutant bacteria were created by knocking out or inactivating one or more genes preferably resulting in the chitin catabolic sensor maintaining an activated state. Methods are further provided for converting the N-acetylglucosamine into ethanol by means of a genetically engineered yeast strain which can be optionally co-cultivated with the Vibrionaceae to produce significant yields of ethanol.


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