Company Filing History:
Years Active: 1989
Title: The Innovations of Saul M. Honigberg
Introduction
Saul M. Honigberg is a notable inventor based in New Haven, CT (US). He has made significant contributions to the field of molecular biology, particularly through his innovative patent related to nucleoprotein filaments. His work has implications for various DNA methodologies, showcasing his expertise and creativity in scientific research.
Latest Patents
Honigberg holds a patent for the invention titled "RecA nucleoprotein filament and methods." This patent describes a stable, single-stranded nucleoprotein filament that is specifically designed to complex with target duplex DNA containing a selected base sequence. The filament consists of a single-stranded DNA probe that has a region of homology with the target base sequence, along with RecA protein that is stably bound to the DNA probe using adenosine 5'-(.gamma.-thio)triphosphate. This invention is particularly useful for enriching target duplex DNA, blocking selected restriction endonuclease sites, and facilitating rapid triple-strand synaptic formation in duplex DNA.
Career Highlights
Saul M. Honigberg is affiliated with Yale University, where he continues to engage in groundbreaking research. His work has not only advanced scientific understanding but has also paved the way for new methodologies in DNA analysis and manipulation.
Collaborations
Honigberg has collaborated with esteemed colleagues such as Charles Meyer Radding and Sherman M. Weissman. These partnerships have contributed to the depth and breadth of his research, enhancing the impact of his innovations in the scientific community.
Conclusion
Saul M. Honigberg's contributions to molecular biology through his patent on RecA nucleoprotein filaments exemplify the importance of innovation in scientific research. His work continues to influence methodologies in DNA analysis and enrich the field of molecular biology.