This inventor holds 2 USPTO granted patents. Top assignee: University of Michigan. Active years: 2008-2012.
Location History:
- Darien, CT (US) (2008)
- Chicago, IL (US) (2012)
Company Filing History:
Years Active: 2008-2012
Title: Innovations by Sarah C. Calve
Introduction
Sarah C. Calve is a prominent inventor based in Darien, CT (US). She has made significant contributions to the field of tissue engineering, particularly in the development of skeletal and connective tissue constructs. With a total of 2 patents, her work is paving the way for advancements in regenerative medicine.
Latest Patents
One of her latest patents is titled "System and method for forming skeletal muscle constructs having functional tissue interfaces." This invention involves a system that allows primary muscle cells to be cultured on a substrate without the need for an exogenous scaffold. The cells form a confluent monolayer, and the design includes anchors that facilitate the self-organization of the muscle construct around secondary tissues, such as neural or tendon tissue. This innovative approach results in a three-dimensional skeletal muscle construct that has functional interfaces with secondary tissues.
Another notable patent is "System and method for forming a connective tissue construct." This invention outlines a method for creating a tendon construct in vitro. It involves a substrate with anchors that support fibroblast cells, allowing them to self-organize and form a three-dimensional connective tissue construct. This method eliminates the need for a synthetic matrix, showcasing a natural approach to tissue engineering.
Career Highlights
Sarah C. Calve is affiliated with the University of Michigan, where she continues her research and development in tissue engineering. Her work has garnered attention for its innovative methodologies and potential applications in medical science.
Collaborations
She collaborates with esteemed colleagues, including Ellen M. Arruda and Lisa M. Larkin, who contribute to her research endeavors and enhance the impact of her inventions.
Conclusion
Sarah C. Calve's contributions to tissue engineering through her innovative patents are significant. Her work not only advances scientific understanding but also holds promise for future medical applications.