Location History:
- Arlington, TX (US) (2014)
- Arlington, VA (US) (2017)
Company Filing History:
Years Active: 2014-2017
Title: Sanjay Awashti: Innovator in Biologic Modifications
Introduction
Sanjay Awashti is a notable inventor based in Arlington, VA (US). He has made significant contributions to the field of biologic modifications, particularly in enhancing the activity of compounds under hypoxic conditions. With a total of 2 patents, his work focuses on innovative compositions and methods that target biologic entities effectively.
Latest Patents
Awashti's latest patents include groundbreaking compositions and methods for modifying one or more biologic targets. These targets encompass cells, DNA, proteins, enzymes, and subjects in need of such modifications. The compositions can exist as monomers or multimers and are designed to be active in biologic environments, particularly under hypoxic conditions. This specificity allows for improved targeting of hypoxic biologic entities, such as tumorigenic cells and those undergoing uncontrolled growth. A typical composition comprises a complex with an overall charge of 2+ or greater, featuring at least one ruthenium atom attached to a redox active ligand. This ligand plays a crucial role in maintaining the separation of multiple ruthenium atoms. Additionally, suitable compositions may include a terminal ligand made of a heterocyclic aromatic compound. When administered to a biologic target, these compositions modify the target without the need for additional compounds, showcasing their catalytic and regenerative properties in the presence of a reducing agent.
Career Highlights
Sanjay Awashti is affiliated with the University of Texas System, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in medical and therapeutic fields.
Collaborations
Awashti collaborates with esteemed colleagues, including Frederick M MacDonnell and Thamara K Janaratne, contributing to a dynamic research environment that fosters innovation.
Conclusion
Sanjay Awashti's contributions to biologic modifications through his innovative patents highlight his role as a significant inventor in the field. His work not only advances scientific understanding but also holds promise for future therapeutic applications.