Location History:
- Seoul, KR (1999 - 2001)
- Daejon, KR (2003)
Company Filing History:
Years Active: 1999-2003
Title: **Innovative Contributions of Inventor Sang-Ic Kim in Paclitaxel Production**
Introduction
Sang-Ic Kim, an inventor based in Daejon, South Korea, has made significant contributions to the field of biotechnological innovations, particularly in the mass production of paclitaxel. Holding three patents, his work focuses on optimizing plant cell cultures to enhance the yield of valuable compounds derived from Taxus genus plants.
Latest Patents
One of Sang-Ic Kim's latest patents discusses the "Mass production of paclitaxel by changing the temperature of the medium during the plant cell culture." This inventive method involves cultivating Taxus plant cells at temperatures around 20 to 25°C and then adjusting the temperature to between 26 and 32°C, which leads to an increase in paclitaxel production. Additionally, the patent outlines methods for maximizing production by inoculating cells at high concentrations and adjusting saccharide levels in the medium, paving the way for convenient mass production suitable for industrial applications.
Another notable patent, "Production of taxol from Taxus plant cell culture by adding silver nitrate," details a semi-continuous culture method that significantly boosts taxol production. By incorporating sugar into the culture medium and adding silver nitrate, the process allows for a substantial increase in taxol yield through careful manipulation of the culturing conditions.
Career Highlights
Throughout his career, Sang-Ic Kim has been associated with organizations that prioritize innovative biotechnological research. Notably, he has worked with Samyang Genex Corporation and Samyang Genex Co., where his expertise in plant cell cultivation and pharmacological applications has been instrumental in developing techniques for enhanced compound production.
Collaborations
Sang-Ic Kim has collaborated with fellow researchers, including Hyung-Kyoon Choi and Jeong-Hwan Yun. Their work together exemplifies the spirit of innovation and teamwork that is pivotal in tackling complex challenges in biotechnological advancements.
Conclusion
In summary, Sang-Ic Kim stands out as a notable inventor in the realm of paclitaxel production through his innovative methods of plant cell culture. His patented techniques not only contribute to the scientific community but also have potential industrial applications that can transform the pharmacological landscape. As biotechnological advancements continue to evolve, the contributions of inventors like Sang-Ic Kim remain critical in ensuring the sustainable and efficient production of essential compounds.