Company Filing History:
Years Active: 2021
Title: Sandra Nitsch: Innovator in Epigenetic Modification
Introduction
Sandra Nitsch is a prominent inventor based in Freiburg, Germany. She has made significant contributions to the field of epigenetics, particularly in the development of constructs for gene silencing. Her innovative work has the potential to impact various areas of medical research and treatment.
Latest Patents
Sandra Nitsch holds a patent for a construct designed for epigenetic modification and its application in the silencing of genes. This patent describes a construct composed of several key components: a Krüppel-associated box zinc finger protein or its homolog, a DNA region capable of binding to the target gene, a human DNA methyltransferase DNMT3A or its homolog, and a murine DNA methyltransferase Dnmt3L or its homolog. These components are linked directly or via at least one linker. The construct serves as a designer epigenome modifier that can silence genes coding for proteins in leukocytes, thereby preventing the internalization of HI viruses in immune cells.
Career Highlights
Sandra Nitsch is affiliated with the Albert-Ludwigs-Universität Freiburg, where she conducts her research and development work. Her career is marked by her dedication to advancing the understanding of epigenetic mechanisms and their applications in gene therapy.
Collaborations
Sandra collaborates with notable colleagues, including Toni Cathomen and Claudio Mussolino, who share her passion for innovative research in the field of genetics.
Conclusion
Sandra Nitsch's contributions to epigenetic modification represent a significant advancement in the field of genetics. Her work not only enhances our understanding of gene silencing but also opens new avenues for therapeutic interventions.