Location History:
- Cary, NC (US) (2009)
- Raleigh, NC (US) (2002 - 2022)
Company Filing History:
5 out of 9 
1 out of 36 
1 out of 1 
Years Active: 2002-2022
Title: Innovations of Samuel Perry Yenne
Introduction
Samuel Perry Yenne is a notable inventor based in Raleigh, NC (US). He has made significant contributions to the field of antibacterial compounds, holding a total of 8 patents. His work focuses on methods for identifying and inhibiting the propagation of selected spectrum bacteria.
Latest Patents
One of Yenne's latest patents involves the identification of selected spectrum antibiotics. The methods disclosed in this patent aim to identify antibacterial compounds that inhibit the propagation of specific bacteria. These bacteria utilize unique tRNA to code for amino acids such as Alanine, Methionine, Serine, or Leucine, which are not used by other bacteria. For instance, the selected spectrum bacteria code for Alanine using GCA, while other bacteria use different codons. The methods include determining whether potential inhibitors promote or inhibit the formation of complexes between tRNA and bacterial ribosomes or aminoacyl synthetases. Compounds that affect this complex formation can disrupt protein production, which is essential for bacterial propagation. By selectively targeting these bacteria, the identified compounds can treat or prevent specific infections without harming the normal bacterial flora or causing resistance.
Career Highlights
Throughout his career, Samuel Perry Yenne has worked with several companies, including Trana Discovery, Inc. and Rhone-Poulenc Agro. His experience in these organizations has contributed to his expertise in the field of antibacterial research.
Collaborations
Yenne has collaborated with notable individuals such as Richard H. Guenther and Winnell H. Newman. These collaborations have further enriched his research and innovations in antibacterial compounds.
Conclusion
Samuel Perry Yenne's contributions to the field of antibacterial research are significant and impactful. His innovative methods for identifying and inhibiting specific bacteria showcase his dedication to advancing medical science.