Samira Kiani

Title: Samira Kiani: Innovator in Synthetic Liver Organoids and Gene Therapy

Introduction

Samira Kiani is a prominent inventor based in Pittsburgh, PA (US), known for her groundbreaking work in the field of synthetic biology. With a total of 7 patents to her name, she has made significant contributions to the development of innovative solutions in organoid technology and gene therapy.

Latest Patents

Among her latest patents is the development of next-generation designer liver organoids and their methods of preparation and use. This patent focuses on synthetic liver organoids and their applications in drug discovery and modeling human liver development. The methods provided enable the production and utilization of synthetic mature liver organoids that comprise functional cells found in the human liver. Another notable patent addresses modulating the human Cas9-specific host immune response. This patent outlines methods and compositions aimed at reducing undesirable T cell immune responses in patients prior to and during gene therapy utilizing CRISPR/Cas9-based genetic modulation.

Career Highlights

Samira Kiani has held positions at esteemed institutions such as Arizona State University and The Johns Hopkins University. Her work has been pivotal in advancing the understanding and application of synthetic organoids in medical research and therapeutic interventions.

Collaborations

Throughout her career, Kiani has collaborated with notable colleagues, including Mo Reza Ebrahimkhani and Farzaneh Moghadam. These partnerships have further enriched her research and contributed to the success of her innovative projects.

Conclusion

Samira Kiani's contributions to the fields of synthetic biology and gene therapy exemplify her commitment to advancing medical science. Her innovative patents and collaborative efforts continue to pave the way for future breakthroughs in healthcare.