Sam Smith

Title: Sam Smith, Inventor in Little Rock, Arkansas.

Introduction

Sam Smith is an inventor associated with the University of Arkansas in Little Rock, Arkansas. His work includes a patent addressing a potential approach to preventing bacterial infections by blocking bacterial adhesion to host cells.

Latest Patents

Smith is associated with 1 patent, titled “Inhibition of bacterial binding by high-mannose oligosaccharides.” The invention describes using high-mannose-containing oligosaccharides, specifically Man₉(GlcNAc)₂-hydrophobic glycopeptides such as tyrosinamide, to interfere with the binding of bacterial pili to oligosaccharides on host-cell plasma membranes. The proposed method targets infections involving *Enterobacter cloacae* and other *Enterobacter* and gram-negative bacterial species.

Career Highlights

Smith’s listed patent connects his inventive work with research at the University of Arkansas. The invention focuses on a molecular strategy for inhibiting bacterial attachment, a process relevant to the treatment of gram-negative bacterial infections.

Collaborations

Smith’s listed coworkers include Y. T. Pan and Alan D. Elbein, who are associated with the research behind the patent.

Conclusion

Sam Smith’s patent reflects research into using high-mannose oligosaccharides to block bacterial adhesion, with the University of Arkansas and his listed collaborators connected to this work.