The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 1999
Filed:
Sep. 18, 1997
Applicant:
Inventors:
Sam Smith, Little Rock, AR (US);
Alan D Elbein, Little Rock, AR (US);
Y T Pan, Little Rock, AR (US);
Assignee:
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C12Q / ;
U.S. Cl.
CPC ...
435-732 ; 435-72 ; 435 32 ;
Abstract
The present invention describes a method for the treatment of gram-negative bacterial infections using high-mannose containing oligosaccharides. Specifically the use of Man.sub.9 (GlcNAc).sub.2 -hydrophobic glycopeptides (i.e. tyrosinamide) to block adhesion of the bacteria pili to the oligosaccharide of the host cells plasma membrane in infections of Enterobacter cloacae and other Enterobacter and gram-negative species.