Company Filing History:
Years Active: 2018
Title: Sabrina Funke: Innovator in Gene Transfer Technology
Introduction
Sabrina Funke is a prominent inventor based in Darmstadt, Germany. She has made significant contributions to the field of gene transfer technology, particularly through her innovative work on retroviral vectors. Her research has the potential to impact various applications in gene therapy and biotechnology.
Latest Patents
Sabrina Funke holds a patent titled "Pseudotyping of retroviral vectors, methods for production and use thereof for targeted gene transfer and high throughput screening." This invention focuses on the pseudotyping of retroviral vectors using heterologous envelope proteins derived from the Paramyxoviridae family. The patent highlights the unexpected finding that incorporating F and H proteins with truncated cytoplasmic tails into lentiviral vector particles enhances the transduction efficiency of cells. Furthermore, these pseudotyped vector particles enable targeted gene transfer by modifying a mutated and truncated H protein with a single-chain antibody or ligand that targets specific cell surface markers.
Career Highlights
Sabrina Funke has established herself as a key figure in her field through her innovative research and patent contributions. Her work has garnered attention for its potential applications in targeted gene therapy, making her a valuable asset in the biotechnology sector.
Collaborations
Sabrina has collaborated with notable colleagues, including Christian Buchholz and Klaus Cichutek. These partnerships have furthered her research and contributed to advancements in gene transfer technologies.
Conclusion
Sabrina Funke's innovative work in gene transfer technology exemplifies the impact of her research on the field. Her patent on retroviral vectors showcases her commitment to advancing biotechnology and gene therapy applications.