S Mariana Margarit

Title: S Mariana Margarit: Innovator in Ras-Sos Complex Research

Introduction

S Mariana Margarit is an accomplished inventor based in Setauket, NY (US). He has made significant contributions to the field of biochemistry, particularly in the study of protein complexes. With a total of 2 patents, Margarit has focused on developing methods that can potentially inhibit tumor proliferation.

Latest Patents

Margarit's latest patents include the "Crystal of a Ras-Sos complex and methods of use thereof." This invention provides a detailed three-dimensional structure for the complex formed between Ras and the Son of sevenless (Sos) protein. The crystals of this complex are also included in the invention. The present invention further provides procedures for identifying agents that can inhibit tumor proliferation through the use of rational drug design predicated on the crystals and crystallographic data disclosed. Another patent titled "Crystal of a Ras-Sos complex" reiterates the same detailed structure and methods for identifying potential tumor inhibitors.

Career Highlights

Throughout his career, S Mariana Margarit has worked with prestigious institutions such as The Rockefeller University and the State University of New York. His research has been pivotal in advancing our understanding of protein interactions and their implications in cancer treatment.

Collaborations

Margarit has collaborated with notable colleagues, including Ann Boriack-Sjodin and Dafna Bar-Sagi, who have contributed to his research endeavors.

Conclusion

S Mariana Margarit is a notable inventor whose work on the Ras-Sos complex has the potential to impact cancer research significantly. His innovative approaches and collaborations continue to pave the way for advancements in the field.