Ryszard Bugno

Title: Ryszard Bugno: Innovator in Serotonin Receptor Research

Introduction

Ryszard Bugno is a notable inventor based in Cracow, Poland. He has made significant contributions to the field of pharmacology, particularly in the development of compounds that interact with serotonin receptors. His work is essential for advancing treatments for various central nervous system disorders.

Latest Patents

Ryszard Bugno holds a patent for "Imidazolyl-substituted indole derivatives binding 5-HT7 serotonin receptor and pharmaceutical compositions thereof." This invention relates to a new class of substituted indole derivatives that activate the 5-HT serotonin receptor. These compounds exhibit high affinity and selectivity for the receptor while possessing favorable physicochemical properties. Notably, they are the first described low-basicity 5-HT receptor agonists. The invention also encompasses the use of these compounds in treating or preventing 5-HT receptor-related disorders, particularly those affecting the central nervous system. Additionally, it includes isotopically labeled compounds for in vivo diagnostics or imaging of the 5-HT serotonin receptor.

Career Highlights

Ryszard Bugno is affiliated with the Institute of Pharmacology of the Polish Academy of Sciences. His research has focused on the development of innovative pharmaceutical compositions that target serotonin receptors, contributing to the understanding and treatment of related disorders.

Collaborations

Ryszard has collaborated with notable colleagues, including Adam Hogendorf and Agata Hogendorf. Their joint efforts have furthered research in pharmacology and the development of new therapeutic agents.

Conclusion

Ryszard Bugno's work in serotonin receptor research exemplifies the importance of innovation in pharmacology. His contributions are paving the way for new treatments that can significantly impact patient care.