Location History:
- Tewsbury, MA (US) (2002)
- Tewksbury, MA (US) (1999 - 2005)
Company Filing History:
3 out of 14 
2 out of 93 
Years Active: 1999-2005
Title: Ruth A Kaplan: Innovator in Immunology and Stem Cell Research
Introduction
Ruth A Kaplan is a prominent inventor based in Tewksbury, MA (US), known for her significant contributions to immunology and stem cell research. With a total of three patents to her name, she has made remarkable advancements in the field of medical science.
Latest Patents
One of her latest patents is the LO-CD2a antibody and its uses for inhibiting T cell activation and proliferation. This invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope to prevent and inhibit an immune response in human patients. The administration of an effective amount of the LO-CD2a antibody can prevent or inhibit graft rejection, graft versus host disease, or autoimmune disease. Another notable patent is the Porcine Oct-4 promoter, which provides a method for isolating and propagating porcine stem cells, specifically pluripotential porcine embryonic stem cells. This invention allows for the survival and growth of these cells through the use of a selectable marker gene regulated by a control or promoter polynucleotide sequence.
Career Highlights
Ruth has worked with several organizations throughout her career, including Biotransplant, Inc. and Université Catholique De Louvain. Her work has significantly impacted the fields of immunology and regenerative medicine.
Collaborations
Ruth has collaborated with notable individuals in her field, including Dominique Latinne and Thomas Kieber-Emmons. These collaborations have furthered her research and innovations.
Conclusion
Ruth A Kaplan is a distinguished inventor whose work in immunology and stem cell research has led to groundbreaking patents. Her contributions continue to influence the medical field and pave the way for future innovations.