The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 01, 2005
Filed:
Jul. 18, 1997
Hervé Bazin, Brussells, BE;
Dominique Latinne, Brussels, BE;
Ruth Kaplan, Tewksbury, MA (US);
Thomas Kieber-emmons, Newton Square, PA (US);
Christina E. Postema, Charlestown, MA (US);
Mary E. White-scharf, Winchester, MA (US);
Hervé Bazin, Brussells, BE;
Dominique Latinne, Brussels, BE;
Ruth Kaplan, Tewksbury, MA (US);
Thomas Kieber-Emmons, Newton Square, PA (US);
Christina E. Postema, Charlestown, MA (US);
Mary E. White-Scharf, Winchester, MA (US);
Universite Catholique de Louvain, Louvain-la-Neuve, BE;
BioTransplant, Inc., Charlestown, MA (US);
Abstract
The present invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.