Company Filing History:
3 out of 15,475 
2 out of 29 
Years Active: 2017-2024
Title: Innovations of Russell E Vance
Introduction
Russell E Vance is a notable inventor based in Albany, CA (US). He has made significant contributions to the field of immunology, particularly in the development of methods and compositions that enhance the production of type I interferon in cells. With a total of 3 patents, Vance's work has implications for therapeutic strategies in treating various diseases.
Latest Patents
One of his latest patents is titled "Cyclic di-nucleotide induction of type I interferon." This invention provides methods and compositions for increasing the production of type I interferon (IFN) in a cell. The methods involve elevating the level of a 2′-5′ phosphodiester linkage comprising cyclic-di-nucleotide in a cell, which is sufficient to boost IFN production. Additionally, Vance has developed compositions and kits for practicing these methods.
Another significant patent is "Compositions and methods for activating 'stimulator of interferon gene'-dependent signalling." This invention presents highly active cyclic-di-nucleotide (CDN) immune stimulators that activate dendritic cells (DCs) through a cytoplasmic receptor known as STING (Stimulator of Interferon Genes). The CDNs in this invention are provided in a composition that includes one or more cyclic purine dinucleotides, which induce STING-dependent type I interferon production.
Career Highlights
Russell E Vance has worked with prestigious institutions, including the University of California and Aduro Biotech Inc. His research has focused on enhancing immune responses, which is crucial for developing new therapeutic approaches.
Collaborations
Throughout his career, Vance has collaborated with notable individuals such as Thomas W Dubensky, Jr. and David Braun Kanne. These collaborations have contributed to the advancement of his research and innovations.
Conclusion
Russell E Vance's contributions to immunology through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to influence the development of new therapeutic strategies for various diseases.