Location History:
- Xinchang, CN (2008)
- Xinchang County, CN (2013 - 2014)
- Zhejiang, CN (2004 - 2015)
- Chengguan Town, CN (2015)
Company Filing History:
6 out of 33 
3 out of 6 
2 out of 2 Years Active: 2004-2015
Title: Runpu Shen: Innovator in Pharmaceutical Synthesis
Introduction
Runpu Shen is a notable inventor based in Zhejiang, China, recognized for his contributions to the field of pharmaceutical synthesis. With a total of nine patents to his name, he has made significant advancements in the preparation of key intermediates used in the production of important pharmaceutical compounds.
Latest Patents
One of his latest patents is a method for preparing 2,6,10-Trimethyl-1,1-dialkoxy-3,5,9-undecatriene, which serves as an intermediate for lycopene. This innovative synthetic method addresses the challenges associated with existing methods, particularly the difficulty in obtaining the raw material dialkyl 4-methyl-5,5-diakoxy-1-pentene-1-phosphonate. The process involves a condensation step where a starting C10-phosphonate is converted to its carbanion under specific conditions, followed by the addition of C4-dialkyl to undergo Wittig-Horner condensation. This method is characterized by its simplicity, accessibility to raw materials, and cost-effectiveness, making it valuable for industrial applications.
Another significant patent involves a linezolid intermediate and the method for synthesizing linezolid. The preparation method features a condensation reaction that yields a high product yield with minimal side reactions. This innovation further showcases Runpu Shen's expertise in developing efficient synthetic pathways for pharmaceutical compounds.
Career Highlights
Throughout his career, Runpu Shen has worked with several prominent companies, including Zhejiang Medicine Co., Ltd., Xinchang Pharmaceutical Factory, and Shaoxing University. His experience in these organizations has contributed to his extensive knowledge and expertise in pharmaceutical synthesis.
Collaborations
Runpu Shen has collaborated with notable colleagues such as Weidong Ye and Xuejun Lao, further enhancing his research and development efforts in the field.
Conclusion
Runpu Shen's innovative work in pharmaceutical synthesis has led to the development of valuable methods and intermediates that are essential for the production of important drugs. His contributions continue to impact the pharmaceutical industry positively.