Hockessin, DE, United States of America

Ruiqin Liu


Average Co-Inventor Count = 9.2

ph-index = 2

Forward Citations = 22(Granted Patents)


Company Filing History:


Years Active: 2001-2007

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6 patents (USPTO):

Title: Innovations and Contributions of Inventor Ruiqin Liu

Introduction

Ruiqin Liu is a notable inventor based in Hockessin, Delaware, with a significant contribution to the field of biochemistry and proteomics. He holds a total of six patents, showcasing his innovative approach to understanding and manipulating biological processes.

Latest Patents

Among his latest patents, one invention focuses on "Assays and peptide substrate for determining aggrecan degrading metallo protease activity." This invention is directed to assays that determine the presence or absence of proteins exhibiting aggrecanase or ADMP activity. It also relates to peptides that act as substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity. Another significant patent is "Antibodies to aggrecan-degrading metalloprotease and diagnostic methods using same." This invention encompasses a family of aggrecan degrading metallo proteases (ADMPs) that can cleave the aggrecan core protein between amino acid residues Glu-Ala. It includes nucleic acids encoding such enzymes, processes for producing recombinant ADMPs, compositions containing these enzymes, and their use in various assays and for developing novel inhibitors for therapies related to aggrecanase-mediated degradation of cartilage or other associated diseases.

Career Highlights

Ruiqin Liu has worked with prominent companies in the pharmaceutical industry, including Bristol-Myers Squibb Company. His experience in these organizations has contributed to his expertise in the development of innovative solutions in biochemistry.

Collaborations

Throughout his career, Liu has collaborated with esteemed colleagues such as Elizabeth C. Arner and Robert A. Copeland. These collaborations have likely enhanced his research and development efforts in the field.

Conclusion

Ruiqin Liu's contributions to the field of biochemistry through his patents and collaborations highlight his innovative spirit and dedication to advancing scientific knowledge. His work continues to impact the understanding of protease activity and its implications for health and disease.

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