The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2007

Filed:

Oct. 12, 2001
Applicants:

Jeffrey A. Miller, Lincoln University, PA (US);

Elizabeth C. Arner, West Grove, PA (US);

Robert A. Copeland, Hockessin, DE (US);

Gary L. Davis, Claymont, DE (US);

Ruiqin Liu, Hockessin, DE (US);

Michael A. Pratta, Glassboro, NJ (US);

Micky D. Tortorella, Newark, DE (US);

Inventors:

Jeffrey A. Miller, Lincoln University, PA (US);

Elizabeth C. Arner, West Grove, PA (US);

Robert A. Copeland, Hockessin, DE (US);

Gary L. Davis, Claymont, DE (US);

Ruiqin Liu, Hockessin, DE (US);

Michael A. Pratta, Glassboro, NJ (US);

Micky D. Tortorella, Newark, DE (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/17 (2006.01); C12N 9/00 (2006.01); C12N 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention is directed to assays to determine the presence or absence of proteins that exhibit aggrecanase or ADMP activity. This invention also relates to peptides that acts as a substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity.


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